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Home > Products >  high purity medetomidine hydrochloride

high purity medetomidine hydrochloride CAS NO.86347-15-1

  • FOB Price: USD 1 /Kilogram Get Latest Price
  • Min.Order: 10 Gram
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    AAAAA(1-100)KilogramAAAAA(1-100)Kilogram

  • Product Details

Keywords

  • medetomidine hydrochloride
  • 37148-47-3
  • Medetomidine

Quick Details

  • ProName: high purity medetomidine hydrochloride
  • CasNo: 86347-15-1
  • Molecular Formula: C13H17ClN2
  • Appearance: solid
  • Application: collodion ,nitrocellulose, varnish,art...
  • DeliveryTime: 3 days after payment confirmation
  • PackAge: According to your request
  • Port: Shanghai
  • ProductionCapacity: 1 Metric Ton/Month
  • Purity: more than 99.6%
  • Storage: Dry and ventilated
  • Transportation: We can send it via HKems, HK Air Post,...
  • LimitNum: 10 Gram
  • Related Substances: 0.001%
  • Residue on Ignition: 0.001%
  • Heavy Metal: 0.001%
  • Valid Period: 0.001%
  • Place of origin: China

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We are specializing in the production of research and development of pharmaceutical intermediates,welcomed the new and old customers advisory purchase,companies invest large fund and brain research fine chemical r&d department,biochemical,phamaceutical and intermediate products to meet the demand of the market .High level research team,advanced equipment and good scientific atmosphere ensure the quality .

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Details

 Medetomidine (hydrochloride) Biological Activity

Description Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.Target: Adrenergic alpha-2 ReceptorMedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. Medetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice [2]. Medetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks [3].
Related Catalog
Solvent
In Vitro:

: ≥ 50 mg/mL (211.20 mM)

* "≥" means soluble, but saturation unknown.

Solubility
1 mM 4.2240 mL 21.1202 mL 42.2404 mL
5 mM 0.8448 mL 4.2240 mL 8.4481 mL
10 mM 0.4224 mL 2.1120 mL 4.2240 mL
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping Room temperature in continental US; may vary elsewhere
SMILES CC(C1=CN=CN1)C2=CC=CC(C)=C2C.Cl
References

[1]. Davies, M.F., et al., Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology, 2004. 29(2): p. 229-39.

[2]. Ozdogan, U.K., et al., The involvement of alpha 2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice. Eur J Pharmacol, 2004. 497(2): p. 161-71.

[3]. Menon, D.V., et al., Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans. J Am Coll Cardiol, 2007. 50(7): p. 626-33.

Related Molecules Isoprenaline hydrochloride | ICI 118,551 (hydrochloride) | Phenylephrine hydrochloride | Yohimbine hydrochloride | L(-)-Epinephrine | Ivabradine hydrochloride | Prazosin hydrochloride |Clenbuterol hydrochloride | Phentolamine mesilate | guanfacine hydrochloride | pimozide | Sotalol hydrochloride | Carvedilol | Atenolol | Metroprolol succinate
Related Doc

SDS |COA |HNMR |LCMS

*The above documents are provided by Medchemexpress and are for scientific research only.

 Chemical & Physical Properties

Boiling Point 381.9ºC at 760 mmHg
Melting Point 164-166°C
Molecular Formula C13H17ClN2
Molecular Weight 236.740
Flash Point 191.3ºC
Exact Mass 236.108032
PSA 28.68000
LogP 3.98030
Storage condition Refrigerator

 Safety Information

HS Code 2942000000

 

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